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ap endonuclease meaning in Hindi

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ap endonuclease sentence in Hindi
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  1. While in Eukaryotes, there is only one AP endonuclease.
  2. Specifically, CSB stimulates the AP site incision activity of AP endonuclease independent of ATP.
  3. This relationship suggested that AP endonuclease originated from a retrotransposon insertion either nearby or within a Helitron.
  4. The AP endonuclease recognizes this sugar and essentially cuts the DNA at this site and then allows for DNA repair to continue.
  5. The AP site can then be cleaved by an AP endonuclease, leaving 3'hydroxyl and 5'deoxyribosephosphate termini ( see DNA structure ).
  6. AP endonuclease, specifically, catalyzes the incision of DNA exclusively at AP sites, and therefore prepares DNA for subsequent excision, repair synthesis and DNA ligation.
  7. Human AP Endonuclease 2 ( APE2 ), like most AP endonucleases, is also of class II . The exonuclease activity of APE2 is strongly dependent upon metal ions.
  8. Previous phylogenetic studies showed that the AP endonuclease is nested within the Chicken Repeat 1 ( CR1 ) clade of non-long terminal repeat ( non-LTR ) retrotransposons.
  9. AP Endonuclease, specifically, catalyze the incision of DNA exclusively at AP sites, and therefore prepare DNA for subsequent excision, repair synthesis and DNA ligation ( 1 ).
  10. APE1 exhibits robust AP-endonuclease activity, which accounts for > 95 % of the total cellular activity, and APE1 is considered to be the major AP endonuclease in human cells.


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